Robert Mauck, PhD

Director of Knowledge Transfer | Working Group 3 Co-Leader | Principal Investigator

Robert Mauck, Ph.D., is the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery and Professor of Bioengineering at the University of Pennsylvania. He is the Director of the McKay Orthopaedic Research Laboratory and the Biomechanics Core of the Penn Center for Musculoskeletal Disorders. Dr. Mauck co-directs the Program in Musculoskeletal Regeneration in the Penn Institute for Regenerative Medicine. Mauck is a Research Health Scientist at the Philadelphia VA Medical Center, and co-Director of the Translational Musculoskeletal Research Center (TMRC) at the VA.

Mauck also serves Co-Leader of Working Group 3 for the Center for Engineering MechanoBiology.

The  Mauck Lab research program in soft tissue mechanobiology and tissue engineering aims to understand the physiologic and patho-physiologic processes that regulate the formation, maturation, and adult function of soft connective tissues. His group focuses on the engineering of musculoskeletal tissues, with a particular interest in restoring articular cartilage, the knee meniscus, and the intervertebral disc. Dr. Mauck’s team uses rigorous mechanical and molecular analyses to characterize native tissue structure and function and employs this information to enhance the functional properties of engineered constructs through focused technology development. Specifically, this work employs adult mesenchymal stem cells, custom mechanobiologic culture conditions, and novel cell scaffolding technologies.

Visit the Mauck Lab website.

Keywords: soft tissue mechanobiology; physiologic processes; patho-physiologic processes; tissue engineering; technological development; mesenchymal stem cells; mechanobiologic cultures; cell scaffolding; mechanobiology

Working Group(s):  Working Group 2: How do cells adapt to and change their mechanical environment?; Working Group 3: How do cells remember their mechanical environment?; Working Group 4: Crosscutting and Emerging Technologies