The Center for
Engineering MechanoBiology

Understanding and harnessing the power of mechanics in tissue, cell, and molecule behavior across the plant and animal kingdoms

Source: Melike Lakadamyali, UPenn, 2020. Super-resolution image of histone and DNA organization in mesenchymal stem cells. Link

Innovation at the Interface of
Physical and Biological Sciences

The Center for Engineering MechanoBiology (CEMB) is a multi-institution Science and Technology Center funded by the National Science Foundation (NSF) to advance the study of mechanical forces in molecules, cells, and tissues in plants and animals.

Committed to inclusion, CEMB recruits, educates, and mentors individuals from all cultural, scientific, and socio-economic backgrounds.

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CEMB_STC
CEMB @cemb_stc ·
20 Mar

Seeking later-stage PhD students & Postdocs to speak at our #FutureLeaders in #Mechanobiology Series for the next year! It's a great chance to make connections, share your work & practice your research talks!

Nominate yourself or your colleagues here: https://bit.ly/CEMB-Future-Leader-Nominations

CEMB @cemb_stc ·
18 Mar

What a great surprise to see our RET alum, Judy, at the #PRISE fair!! Loved hearing how she's implemented #mechbio and #modeling in her HS classes.

Find out more about our #RET program: http://bit.ly/3ws3SQ8

CEMB @cemb_stc ·
16 Mar

Just accepted @Biofabrication! Fabrication of dogbone-shaped meniscal constructs led by @BurdickLab, in collaboration with @MauckLab and @HeoLab. Let's congratulate the lead author, @mprend22 and the team! https://iopscience.iop.org/article/10.1088/1758-5090/acc3c3/meta

CEMB @cemb_stc ·
16 Mar

Ever imagined how plants can help with surgery? Check out the eureka moment behind the plant-inspired surgical technique for reattaching tendons to bone, by @GeninLab @WUSTL, @ThomopoulosLab @OrthoColumbia and the late, inspiring Barbara Pickard https://engineering.wustl.edu/news/2023/Hitchhiker-plants-inspire-improved-techniques-for-reattaching-tendon-to-bone.html

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Joel Boerckel @jboerckel ·
14 Mar

I was waiting to tweet about this til after the reviews came back, but the time is ripe.

We sent this paper to @eLife because I fundamentally believe in the value of experimentation - in science and in Science. 1/ https://twitter.com/jboerckel/status/1537980273589047300

Joel Boerckel @jboerckel

Our latest @biorxivpreprint, from Devon Mason, is live today!

Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis
https://www.biorxiv.org/content/10.1101/2022.06.15.496293v1

A paper thread:

Engineering Mechano-Intelligence

We seek to study, understand, and engineer the working memory of cells to enhance their function and environmental fitness.

Source: Kara McCloskey, UC, Merced, 2019. This is an image of vascular progenitor cells differentiating into patterned vascular cells.

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Annual Mechanobiology Symposium

Save the Date!

The 5th Annual Mechanobiology Symposium: MechanoImmunology and Epigenetics will be on April 4 & 5, at University of Pennsylvania (Philadelphia, PA) and virtually! Register now!