The Center for
Engineering MechanoBiology

Understanding and harnessing the power of mechanics in tissue, cell, and molecule behavior across the plant and animal kingdoms

Source: Melike Lakadamyali, UPenn, 2020. Super-resolution image of histone and DNA organization in mesenchymal stem cells. Link

Innovation at the Interface of
Physical and Biological Sciences

The Center for Engineering MechanoBiology (CEMB) is a multi-institution Science and Technology Center funded by the National Science Foundation (NSF) to advance the study of mechanical forces in molecules, cells, and tissues in plants and animals.

Committed to inclusion, CEMB recruits, educates, and mentors individuals from all cultural, scientific, and socio-economic backgrounds.

Engineering Mechano-Intelligence

We seek to study, understand, and engineer the working memory of cells to enhance their function and environmental fitness.

Source: Kara McCloskey, UC, Merced, 2019. This is an image of vascular progenitor cells differentiating into patterned vascular cells.

Research That Drives Results

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Startups + Patents


Access resources for high school
students, undergraduates,
and graduate students

Startups + Enterprises

Learn about research and licensing
for startups and businesses of
all sizes


Meet the faculty, researchers, and
trainees working to advance
our mission

Annual Mechanobiology Symposium

Image of 2023 Symposium poster

The 6th Annual Mechanobiology Symposium + Retreat: Mechanointelligence was held on March 5 & 6, 2024, at University of Pennsylvania (Philadelphia, PA) and featured over 10 speakers from around the world.