The Center for
Engineering MechanoBiology

Understanding and harnessing the power of mechanics in tissue, cell, and molecule behavior across the plant and animal kingdoms

What is mechanobiology?
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Source: Melike Lakadamyali, UPenn, 2020. Super-resolution image of histone and DNA organization in mesenchymal stem cells. Link

Innovation at the Interface of
Physical and Biological Sciences

The Center for Engineering MechanoBiology (CEMB) is a multi-institution Science and Technology Center funded by the National Science Foundation (NSF) to advance the study of mechanical forces in molecules, cells, and tissues in plants and animals.

Committed to inclusion, CEMB recruits, educates, and mentors individuals from all cultural, scientific, and socio-economic backgrounds.

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Commitment to Diversity

Do NOT miss this outstanding talk by @LianaBoraas (@NicoliLab @Yale) from our #FutureLeaders in #Mechanobiology series!

Watch it now! "Untranslated mRNA sequences regulate cell movement via a non-coding function":

#mRNA #FocalAdhesions #G3BP1

Our last *virtual* info session for CEMB's #UndergradResearch #gradschool and #masters fellowships is tomorrow, 11/22 at 12pm ET!

Log in to learn about all that CEMB does in #research and opportunities for you!

Register here:


Applications are NOW OPEN for the #CEMB summer undergrad research program #UExB! Encourage the sophomores and juniors you know to apply!
Full details:
Want to learn more? Join us at two virtual info sessions on 11/16 & 11/22:

Our paper on the integrity of endothelial junctions led by
@Eoin_McEvoy was just published in Nature Communications! Our theory predicts that junctions are most stable at optimum levels of contractility and polymerization. @PennEngineers @CEMB_STC

“We are seeking to employ an excellent postdoc to work on a disease modeling  project using human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs)  to model conditions known as the Rasopathies, in particular Neurofibromatosis 1 and Noonan syndrome”.

Our lab has a postdoc fellow position available, with focus on ion channels and calcium signaling in normal and diseased skeletal muscle. #calcium#postdocposition#lyon

Engineering Mechano-Intelligence

We seek to study, understand, and engineer the working memory of cells to enhance their function and environmental fitness.

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Source: Kara McCloskey, UC, Merced, 2019. This is an image of vascular progenitor cells differentiating into patterned vascular cells.

Research That Drives Results

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Annual Mechanobiology Symposium

4th Annual Symposium Draft_banner_v1
Save the Date!

The 4th Annual Mechanobiology Symposium: Mechanobiology and Metabolism will be on March 9 and 10, 2022, at University of Pennsylvania (Philadelphia, PA) and virtually! Stay tuned for registration information.

Mechanobiology Symposium