Congratulations to Yale E. Goldman for winning the Biophysical Society’s 2020 Kazuhito Kinosita Award in Single Molecule Biophysics. This award is in recognition of Yale’s seminal contributions in measuring and understanding orientations, rotations, and dynamics of motor proteins by developing and using single molecule imaging approaches.  Three papers significant to the award are listed below.  The award will be presented at the Biophysical Society meeting in San Diego on February 18th.

 

Figure 1.  Myosin biochemical model and example UFFC traces. (from Woody et al.)

Woody et al. 2019.  Single molecule mechanics resolves the earliest events in force generation by cardiac myosin. eLife 2019;8:e49266 DOI: 10.7554/eLife.49266

Chen et al. 2016.  Elongation factor G initiates translocation through a power stroke.  PNAS, 113 (27): 7515-7520.  www.pnas.org/cgi/doi/10.1073/pnas.1602668113

Forkey et al. 2003.  Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization.  Nature, 422;399-404.