In a recent paper published in Hepatology, CEMB’s Rebecca G. Wells, reports on creating the first bile duct-on-a-chip, making it possible for more-complete research to be conducted without the need for human or animal participants. “Bile ducts pose great challenges to researchers because of their location and their complex function and cellular structure, which has […]
Plant biologist Lucia Strader in the School of Arts & Sciences at Washington University in St. Louis discovered a cellular transporter that regulates root initiation and progression. Roots anchor plants in place and allow them to absorb nutrient from soil. But the process of growing new roots is costly to a plant, and there can […]
Dan Huh, the Wilf Family Term Assistant Professor in the Department of Bioengineering, focuses his research on creating organs-on-chips: specially manufactured micro-devices with human cells that mimic the natural cellular processes of organs. Recently, the lab has engineered chips that approximate the functioning of the eye, a placenta and a diseased lung. ...
From Penn Today: June 6, 2019: To treat large gaps in long bones, like the femur, which result from bone tumor removal or a shattering trauma, researchers Joel Boerckel’s group and the University of Illinois at Chicago developed a process that partially recreates the bone growth process that occurs before birth. A bone defect of more […]
As stem cells differentiate into functional specialized cells, the process is controlled through signals from their surroundings. In a recent paper published in Nature Materials, this CEMB study suggests that cells may have more control over their fate than previously thought. The study found that cells secrete proteins within hours of being encapsulated in specialized […]
The Lush Prize is a major initiative aiming to bring forward the day when safety testing takes place without the use of animals. It focuses pressure on toxicity testing for consumer products and ingredients, in a way which complements the many projects already addressing the use of animals in medical testing. The Lush Prize rewards […]
(News item prepared by Patience Graybill, Wash U) Researchers have thought that cancer begins when a single cell goes rogue in the body then begins to grow and multiply. Now, they are investigating evidence of more damage when a group of cells breaks off from a colony and more follow, leading to large-scale metastasis. Amit […]
A system of interconnected, fluid-filled compartments lies below the skin’s surface, lining the digestive tract, lungs and urinary systems, and around arteries, veins, and the space between muscles, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, Mount Sinai Beth Israel Medical Center, and the New York University School of […]
Congrats to CEMB PIs Vivek Shenoy, Jason Burdick, Paul Janmey, and Robert Mauck and their new publication on how matching material and cellular timescales effects cell spreading in viscoelastic substrates. Read more in the Proceedings of the National Academy of Sciences.
Two new publications from the lab of Ram Dixit at Washington University in St. Louis indicate how kinesin motor proteins and the microtubule tracks on which they move are regulated in plant cells. Kinesins are proteins that work as “engines” that carry material from one part of the cell to the next. As a transporter […]