Research News

Hold the Date – Annual Symposium – January 28, 2021

By James McGonigle on November 12, 2020

3rd Annual Mechanobiology Symposium The focus of the symposium will be “Engineering Mechano-Intelligence,” organized around three sessions:  1) Cell-Matrix Dialogue, 2) The Nucleus and Mechanical Memory, and 3) Tissue Mechanics in 4D.  The symposium will be held on-line on a remote platform for all participants.  

CEMB Team Uses Magnetic Fields to Regrow Cartilage Tissue

By James McGonigle on November 11, 2020

Robert Mauck and Xuemei Cheng have collaborated on a recent study published in Advanced Materials that demonstrates how magnetic fields and hydrogels can grow new joint cartilage. The technique produces cartilage tissue that bonds with bone and may lead to new treatments for age-related injuries.   READ MORE

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Mechanobiology Collection in Biophysical Journal

By Annie Jeong on June 25, 2020

CEMB Director Vivek Shenoy has curated a collection of recent, cross-kingdom mechanobiology published papers in Biophysical Journal: In this collection we have selected papers published in Biophysical Journal during the past year that focus on different aspects of mechanobiology. These articles highlight the cross-kingdom importance of mechanobiology, spanning shape evolution in plant organs and migration of single […]

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When it Rains……. It Swells.

By James McGonigle on June 24, 2020

Elizabeth Haswell, PhD and professor of biology at Washington University in St. Louis and postdoctoral research scholar, Dabarati Basu have discovered the mechanosensitive ion channels in the plant’s cells that respond to swelling by inducing cell death — potentially to protect the rest of the plant. The discovery — reported by Haswell and Debarati Basu, […]

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Ben Prosser to Co-Lead $6.5 Million Transatlantic Grant to Investigate Cytoskeleton’s Role in Heart Disease

By James McGonigle on June 22, 2020

Benjamin L. Prosser, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania, will serve as the North American coordinator for a new, multi-institutional $6.5 million grant from the Leducq Foundation, aimed at better understanding the role the heart cell cytoskeleton plays in heart disease and finding new ways to […]

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Motor proteins create more stable tracks to deliver much-needed materials in plant cells

By James McGonigle on June 12, 2020

From WashU’s, The Source. June 2, 2020. As a plant grows, it moves cellular material from its version of manufacturing sites to the cell wall construction zone. Transporter proteins, called motor proteins, are thought to move these cell wall cargo via a complex highway system made up of microtubule tracks. The position of these tracks […]

Yale E. Goldman: 2020 recipient of the Kazuhito Kinosita Award in Single-Molecule Biophysics

By James McGonigle on January 27, 2020

Congratulations to Yale E. Goldman for winning the Biophysical Society’s 2020 Kazuhito Kinosita Award in Single Molecule Biophysics. This award is in recognition of Yale’s seminal contributions in measuring and understanding orientations, rotations, and dynamics of motor proteins by developing and using single molecule imaging approaches.  Three papers significant to the award are listed below.  […]

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Remembering Barbara G. Pickard

By James McGonigle on December 23, 2019

With great sadness, we share the loss of our friend, Prof. Barbara G. Pickard of Washington University in St. Louis.  Barbara passed on December 6, 2019, from complications related to hip surgery.   She served as a faculty fellow of CEMB since its inception. Prof. Pickard played a foundational role in ideas that helped shape CEMB, […]

Healing interventions for spinal disc injuries

By James McGonigle on November 18, 2019

Researchers in the Mauck group have discovered that using a biological inhibitor to prevent cells in the spinal cord from becoming stressed and starting a subpar healing process gives doctors more time to treat injuries before they worsen. “These data show us that treating disc injuries very soon after injury is essential before this transition in […]

Why Tissue Gets Stiffer When Compressed

By Annie Jeong on October 16, 2019

In a study recently published in Nature, Drs. Paul Janmey and Vivek Shenoy, along with their graduate students Anne van Oosten and Xingyu Chen and collaborators, have answered the long-standing biomedical paradox of why tissues stiffen when compressed.  Reported in The Medium, the researchers found that when tissue is compressed, the cells inside expand laterally, […]