Research News

What I Did for My Summer Vacation!

By James McGonigle on November 7, 2019

by Amanda Cottone and Jim McGonigle.   Our 2019 Summer Research Experience for Teachers program supported its 3rd cohort consisting of four high school STEM teachers from the Philadelphia area. Over the seven-week program, teachers immersed themselves in mechanobiology research at the University of Pennsylvania to engage in a real-world inquiry that marries science and engineering. […]

Why Tissue Gets Stiffer When Compressed

By Annie Jeong on October 16, 2019

In a study recently published in Nature, Drs. Paul Janmey and Vivek Shenoy, along with their graduate students Anne van Oosten and Xingyu Chen and collaborators, have answered the long-standing biomedical paradox of why tissues stiffen when compressed.  Reported in The Medium, the researchers found that when tissue is compressed, the cells inside expand laterally, […]

[img] Rebecca Wells

Organ-Level Function on a Chip: Bile Duct-on-a-Chip

By James McGonigle on October 8, 2019

In a recent paper published in Hepatology, CEMB’s Rebecca G. Wells, reports on creating the first bile duct-on-a-chip, making it possible for more-complete research to be conducted without the need for human or animal participants. “Bile ducts pose great challenges to researchers because of their location and their complex function and cellular structure, which has […]

[img] Lucia Strader

Plant Cell Mechanobiology Blossoming at WashU

By James McGonigle on August 14, 2019

Plant biologist Lucia Strader in the School of Arts & Sciences at Washington University in St. Louis discovered a cellular transporter that regulates root initiation and progression.  Roots anchor plants in place and allow them to absorb nutrient from soil.  But the process of growing new roots is costly to a plant, and there can […]

Trainee Pilot Awards: Proposal Deadline Nears!

By James McGonigle on August 13, 2019

$10K TRAINEE PILOT AWARDS DOWNLOAD GUIDELINES CEMB encourages applications for up to 3 pilot awards of up to $10,000 each to pairs or groups of CEMB-affiliated trainees to carry out innovative and integrative pilot studies in mechanobiology. Open to any CEMB trainee affiliate (postdocs or graduate students) Each proposal must be submitted by a pair […]

Replicating fetal bone growth process could help heal large bone defects

By James McGonigle on June 10, 2019

From Penn Today:  June 6, 2019:  To treat large gaps in long bones, like the femur, which result from bone tumor removal or a shattering trauma, researchers Joel Boerckel’s group and the University of Illinois at Chicago developed a process that partially recreates the bone growth process that occurs before birth. A bone defect of more […]

Cells Control Their Own Fate by Manipulating their Environment

By James McGonigle on April 11, 2019

As stem cells differentiate into functional specialized cells, the process is controlled through signals from their surroundings.  In a recent paper published in Nature Materials, this CEMB study suggests that cells may have more control over their fate than previously thought. The study found that cells secrete proteins within hours of being encapsulated in specialized […]

Faculty promotions at Washington University in St. Louis

By James McGonigle on March 15, 2019

We are thrilled to congratulate two of our colleagues on their promotion to the rank of associate professor with tenure, effective next fall Marcus Foston, Associate Professor in the Department of Energy, Environmental & Chemical Engineering.  BioProducts Engineering Lab. Amit Pathak, Associate Professor in the Department of Mechanical Engineering & Materials Science. Cellular Mechanobiology Laboratory.

[img] Dan Huh

Dan Huh Wins 2018 Lush Science Prize for Organ-on-a-Chip Work

By James McGonigle on February 11, 2019

The Lush Prize is a major initiative aiming to bring forward the day when safety testing takes place without the use of animals.  It focuses pressure on toxicity testing for consumer products and ingredients, in a way which complements the many projects already addressing the use of animals in medical testing.  The Lush Prize rewards […]

[img] Shenoy

Vivek Shenoy receives Heilmeier Research Award

By James McGonigle on January 30, 2019

Heilmeier Awards Committee in Penn Engineering has selected Professor Vivek Shenoy from the Department of Materials Science and Engineering as the recipient of the 2019 Heilmeier Research Award. This award is named for our late alumnus and Overseer George Heilmeier, whose many technological contributions include the development of liquid crystal displays. The distinction associated with the […]